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Reviews provided by RottenTomatoes
Glenn Lovell, San Jose Mercury News: Depending on your age and mindset, the ensuing gastrointestinal skirmish will seem either terribly clever or nauseatingly rude, the potty joke to end all potty jokes. Read more
Terry Lawson, Detroit Free Press: Though juvenile tastelessness continues to run rampant, Osmosis Jones can at least be safely enjoyed by most juveniles, who will also get a valuable lesson in what a lifetime of junk-food abuse can do. Read more
Robert K. Elder, Chicago Tribune: For fans of animation and larger-than-life jokes, Osmosis Jones is just what the doctor ordered. Read more
Susan Stark, Detroit News: In more parts than not, Osmosis Jones is funny as it is fearless. Read more
Tom Maurstad, Dallas Morning News: This live-action/ cartoon structure is intended to give Osmosis Jones an edgy kick. But instead it proves to be a boat anchor around the comedy's neck. Read more
Norman Wilner, Toronto Star: The animated sequences in Osmosis Jones are funny and clever and thoroughly entertaining, with plenty of lively imagination on display in the transposition of a 1970s cop movie to the inner workings of the human body. Read more
Elvis Mitchell, New York Times: Osmosis Jones, with its effluvia-festival brand of humor, is often fun, and the rounded, blobby rendering of the characters is likable. Read more
Mark Rahner, Seattle Times: A very clever, very gross, very funny spoof of the cliched cop genre. Read more
Eric Harrison, Houston Chronicle: Movies are easier to enjoy when you aren't always covering your eyes. Read more
Paul Clinton (CNN.com), CNN.com: Osmosis Jones is pure Farrelly, still pushing the envelope of gross-out humor. Read more
Steven Rosen, Denver Post: I really enjoyed Kroon and Sito's movie, but disliked the Farrellys. It's time they try harder - their style has grown sickening. And it's time Kroon and Sito make both halves of a film. Read more
Lisa Schwarzbaum, Entertainment Weekly: In a business where one hand is always washing the other, anyone who has ever popped a zit has got to admire the boys' clean ability to squeeze new material out of old places. Read more
Liam Lacey, Globe and Mail: As long as Osmosis Jones sticks to the action-flick innards -- from the gangster dens of the armpits to the deportee docks of the bladder -- it's an inventive series of gags (in both senses). Read more
Roger Ebert, Chicago Sun-Times: Likely to entertain kids, who seem to like jokes about anatomical plumbing. For adults, there is the exuberance of the animation and the energy of the whole movie, which is just plain clever. Read more
Wesley Morris, San Francisco Chronicle: Isn't a movie so much as a health-class nutrition lecture. Read more
Time Out: The plot's so much old rote, and the characters have all the personality of protoplasm; but the anthropomorphising of this microcosmic metropolis is wonderfully imaginative, and the dialogue decidedly spiffy. Read more
Claudia Puig, USA Today: Adults might remain immune to the process of Osmosis, but younger viewers probably will be receptive to its nervy fun. Read more
Robert Koehler, Variety: Like the human body it imagines as a sprawling metropolis, Osmosis Jones has some precincts operating at peak efficiency, and others in need of urban renewal. Read more
Michael Atkinson, Village Voice: Not since David Cronenberg's Rabid has a movie used biological vulnerability to such resonant and anxious profit. Read more