Dr. George Coleman is a top veterinarian with an impressive list of famous animal patients at the Crane Animal Hospital—a bustling New York City veterinary practice where it often seems as if the patients are running the place. Much to his chagrin, George recently learned that his ex-girlfriend, Dorothy Crane, has inherited the family business and is now George's boss.

Tagline: It's quite an operation.
Cast:
Justin Kirk Justin Kirk
George Coleman 
JoAnna Garcia Swisher JoAnna Garcia Swisher
Dorothy Crane 
Tyler Labine Tyler Labine
Doug Jackson 
Bobby Lee Bobby Lee
Robert Yamamoto 
Kym Whitley Kym Whitley
Juanita 
Betsy Sodaro Betsy Sodaro
Angela